You Know the Stratford Case is Lost. . .
Shakespeare mentioned sexually transmitted disease (STD) symptoms – and treatments – in several of his plays and poems, including Troilus and Cressida, As You Like It, and Sonnets.
In Shakespeare’s time, one of the treatments for syphilis, inhalation of mercury vapor, was worse than the disease. Ross suggests that Shakespeare’s tremulous signature on his will, his social withdrawal in later years, and even his baldness might all be due to a mild degree of mercury vapor poisoning.
I've got another explanation.